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PDE12 Antikörper (AA 559-609)

PDE12 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7449244
  • Target Alle PDE12 Antikörper anzeigen
    PDE12 (Phosphodiesterase 12 (PDE12))
    Bindungsspezifität
    • 10
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 559-609
    Reaktivität
    • 24
    • 9
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 26
    • 1
    Kaninchen
    Klonalität
    • 27
    Polyklonal
    Konjugat
    • 14
    • 4
    • 3
    • 2
    • 2
    • 2
    Dieser PDE12 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 17
    • 14
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Rabbit anti-PDE12 Antibody, Affinity Purified
    Homologie
    Mouse,Rat,Bovine
    Aufreinigung
    Affinity Purified
    Immunogen
    Between AA 559 and 609
    Isotyp
    IgG
    Top Product
    Discover our top product PDE12 Primärantikörper
  • Applikationshinweise
    1:2,000 - 1:10,000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    PDE12 (Phosphodiesterase 12 (PDE12))
    Andere Bezeichnung
    PDE12 (PDE12 Produkte)
    Synonyme
    2'-PDE antikoerper, E430028B21Rik antikoerper, LRRGT00074 antikoerper, RGD1310975 antikoerper, phosphodiesterase 12 S homeolog antikoerper, phosphodiesterase 12 antikoerper, pde12.S antikoerper, PDE12 antikoerper, pde12 antikoerper, Pde12 antikoerper
    Hintergrund
    Background: PDE12 is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. It also cleaves 3',5'-phosphodiester bond of oligoadenylates and plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system [taken from the Universal Protein Resource (UniProt) Q6L8Q7].
    Gen-ID
    201626
    UniProt
    Q6L8Q7
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