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CD45RO Antikörper

CD45RO Reaktivität: Human WB, IHC, IF (p), ICC, mIF Wirt: Maus Monoclonal UCHL-1 unconjugated
Produktnummer ABIN7449553
  • Target Alle CD45RO Produkte
    CD45RO
    Reaktivität
    • 72
    • 12
    • 12
    • 11
    • 11
    Human
    Wirt
    • 60
    • 12
    Maus
    Klonalität
    • 60
    • 12
    Monoklonal
    Konjugat
    • 11
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD45RO Antikörper ist unkonjugiert
    Applikation
    • 56
    • 29
    • 25
    • 13
    • 12
    • 10
    • 10
    • 9
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Multiplex Immunofluorescence (mIF)
    Verwendungszweck
    Mouse anti-CD45RO Monoclonal Antibody, Purified [UCHL-1]
    Immunogen
    Cultured T-cells from an IL-2-dependent T-cell line (CA1)
    Klon
    UCHL-1
    Isotyp
    IgG
  • Applikationshinweise

    IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 05:10:00

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    Phosphate Buffered Saline (PBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    CD45RO
    Andere Bezeichnung
    CD45RO (CD45RO Produkte)
    Hintergrund
    Background: CD45RO is also known as protein tyrosine phosphatase receptor type C (PTPRC). It is a protein tyrosine phosphatase required for T-cell activation through the antigen receptor. CD45RO acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45RO recruits and dephosphorylates SKAP1 and FYN. It also dephosphorylates LYN, and thereby modulates LYN activity (By similarity)[taken from UniProtKB (Entry: P08575)].
    Gen-ID
    5788
    NCBI Accession
    NP_002829
    UniProt
    P08575
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