Rekombinanter GZMB Antikörper (AA 19-247)
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- Target Alle GZMB Antikörper anzeigen
- GZMB (Granzyme B (GZMB))
- Antikörpertyp
- Recombinant Antibody
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Bindungsspezifität
- AA 19-247
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser GZMB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Multiplex Immunofluorescence (mIF)
- Verwendungszweck
- Rabbit anti-Granzyme B Recombinant Monoclonal Antibody [BLR022E]
- Immunogen
- residues 19-247 (mature protein)
- Klon
- BLR022E
- Isotyp
- IgG
- Top Product
- Discover our top product GZMB Primärantikörper
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- Applikationshinweise
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IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 17:40:00
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- GZMB (Granzyme B (GZMB))
- Andere Bezeichnung
- Granzyme B (GZMB Produkte)
- Synonyme
- CCPI antikoerper, CGL-1 antikoerper, CGL1 antikoerper, CSP-B antikoerper, CSPB antikoerper, CTLA1 antikoerper, CTSGL1 antikoerper, HLP antikoerper, SECT antikoerper, granzyme B antikoerper, GZMB antikoerper
- Hintergrund
- Background: Granzyme B is a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing [taken from NCBI Entrez Gene (Gene ID: 3002)]
- Gen-ID
- 3002
- NCBI Accession
- NP_004122
- UniProt
- P10144
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose
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