FANCB Antikörper (AA 820-859)

Produktnummer ABIN7449654

Produktdetails anti-FANCB Antikörper

Target: FANCB (Fanconi Anemia, Complementation Group B (FANCB))

Bindungsspezifität: AA 820-859

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCB Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-FANCB Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 820 and 859

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 10 μg/mg lysate

WB: Not recommended.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu FANCB

Target: FANCB (Fanconi Anemia, Complementation Group B (FANCB))

Andere Bezeichnung: FANCB (FANCB Produkte)

Hintergrund: Background: FANCB (Fanconi anemia complementation group B) is part of a DNA repair network which involves BRCA1 and BRCA2 and required for the ubiquitination of FANCD2. The FANCB gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. The FANC members are not homologous proteins but are related by their assembly into a common nuclear complex. Defects in FANCB are the cause of Fanconi pancytopenia type 2, Fanconi anemia, and X-linked VACTERL.

Gen-ID: 2187

NCBI Accession: NP_001018123

UniProt: Q8NB91

Pathways: DNA Reparatur