Stim2 Antikörper (AA 650-700)
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- Target Alle Stim2 Antikörper anzeigen
- Stim2 (Stromal Interaction Molecule 2 (Stim2))
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Bindungsspezifität
- AA 650-700
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Stim2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Verwendungszweck
- Rabbit anti-STIM2 Antibody, Affinity Purified
- Aufreinigung
- Affinity Purified
- Immunogen
- Between AA 650 and 700
- Isotyp
- IgG
- Top Product
- Discover our top product Stim2 Primärantikörper
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- Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:5,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- Stim2 (Stromal Interaction Molecule 2 (Stim2))
- Andere Bezeichnung
- STIM2 (Stim2 Produkte)
- Synonyme
- STIM2 antikoerper, stromal interaction molecule 2 antikoerper, STIM2 antikoerper, stim2 antikoerper, Stim2 antikoerper
- Hintergrund
- Background: STIM2 (stromal interaction molecule 2) plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Stim2 functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. It regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, STIM2 translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI. STIM2 may inhibit STIM1-mediated Ca(2+) influx [taken from the Universal Protein Resource (UniProt) Q9P246].
- Gen-ID
- 57620
- NCBI Accession
- NP_065911
- UniProt
- Q9P246
- Pathways
- T-Zell Rezeptor Signalweg, BCR Signaling
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