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Stim2 Antikörper (AA 650-700)

Stim2 Reaktivität: Human, Maus WB, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7449833
  • Target Alle Stim2 Antikörper anzeigen
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Bindungsspezifität
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 650-700
    Reaktivität
    • 37
    • 13
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 35
    • 1
    • 1
    Kaninchen
    Klonalität
    • 37
    Polyklonal
    Konjugat
    • 21
    • 5
    • 4
    • 3
    • 2
    • 2
    Dieser Stim2 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 27
    • 19
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Verwendungszweck
    Rabbit anti-STIM2 Antibody, Affinity Purified
    Aufreinigung
    Affinity Purified
    Immunogen
    Between AA 650 and 700
    Isotyp
    IgG
    Top Product
    Discover our top product Stim2 Primärantikörper
  • Applikationshinweise

    IP: 2 - 10 μg/mg lysate

    WB: 1:1,000 - 1:5,000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Andere Bezeichnung
    STIM2 (Stim2 Produkte)
    Synonyme
    STIM2 antikoerper, stromal interaction molecule 2 antikoerper, STIM2 antikoerper, stim2 antikoerper, Stim2 antikoerper
    Hintergrund
    Background: STIM2 (stromal interaction molecule 2) plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Stim2 functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. It regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, STIM2 translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI. STIM2 may inhibit STIM1-mediated Ca(2+) influx  [taken from the Universal Protein Resource (UniProt) Q9P246].
    Gen-ID
    57620
    NCBI Accession
    NP_065911
    UniProt
    Q9P246
    Pathways
    T-Zell Rezeptor Signalweg, BCR Signaling
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