EPH Receptor A5 Antikörper (AA 451-550)
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- Target Alle EPH Receptor A5 (EPHA5) Antikörper anzeigen
- EPH Receptor A5 (EPHA5)
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Bindungsspezifität
- AA 451-550
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EPH Receptor A5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human, Maus
- Homologie
- Rat,Cow,Pig,Rabbit,Guinea Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human EphA5/Eph receptor A5
- Isotyp
- IgG
- Top Product
- Discover our top product EPHA5 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- EPH Receptor A5 (EPHA5)
- Andere Bezeichnung
- Eph receptor A5 (EPHA5 Produkte)
- Synonyme
- CEK7 antikoerper, EHK-1 antikoerper, EHK1 antikoerper, EK7 antikoerper, HEK7 antikoerper, TYRO4 antikoerper, AI854630 antikoerper, AW125296 antikoerper, Cek7 antikoerper, Ehk1 antikoerper, Els1 antikoerper, Hek7 antikoerper, Rek7 antikoerper, bsk antikoerper, Els1. antikoerper, EPHA5 antikoerper, EPH receptor A5 antikoerper, Eph receptor A5 antikoerper, EPHA5 antikoerper, epha5 antikoerper, Epha5 antikoerper
- Hintergrund
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Synonyms: EK7, CEK7, EHK1, HEK7, EHK-1, TYRO4, Ephrin type-A receptor 5, Brain-specific kinase, EPH homology kinase 1, EPH-like kinase 7, EPHA5, BSK
Background: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity).
- Gen-ID
- 2044
- UniProt
- P54756
- Pathways
- RTK Signalweg
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