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MAML1 Antikörper (AA 75-125)

MAML1 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7449893
  • Target Alle MAML1 Antikörper anzeigen
    MAML1 (Mastermind-Like 1 (MAML1))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 75-125
    Reaktivität
    • 29
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 28
    • 1
    • 1
    Kaninchen
    Klonalität
    • 30
    Polyklonal
    Konjugat
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser MAML1 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 21
    • 13
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Verwendungszweck
    Rabbit anti-MAML1 Antibody, Affinity Purified
    Aufreinigung
    Affinity Purified
    Immunogen
    between AA 75 and 125
    Isotyp
    IgG
    Top Product
    Discover our top product MAML1 Primärantikörper
  • Applikationshinweise

    IP: 2 - 10 μg/mg lysate

    WB: 1:10,000 - 1:25,000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    MAML1 (Mastermind-Like 1 (MAML1))
    Andere Bezeichnung
    MAML1 (MAML1 Produkte)
    Synonyme
    mam1 antikoerper, mam-1 antikoerper, xmam1 antikoerper, MAML1 antikoerper, AI644666 antikoerper, AW743257 antikoerper, D930008C07Rik antikoerper, Mam-1 antikoerper, Mam1 antikoerper, mKIAA0200 antikoerper, mastermind like transcriptional coactivator 1 L homeolog antikoerper, mastermind like transcriptional coactivator 1 antikoerper, mastermind like 1 (Drosophila) antikoerper, mastermind-like transcriptional coactivator 1 antikoerper, maml1.L antikoerper, MAML1 antikoerper, Maml1 antikoerper
    Hintergrund
    Background: There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML1 is a critical coactivator for NOTCH signaling. MAML1 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors. MAML1 has been observed to interact with p300 to acetylate histones H3 and H4. MAML1 also interacts with p53 and functions independent of NOTCH signaling, as a coactivator of p53 target genes.
    Gen-ID
    9794
    NCBI Accession
    NP_055572
    UniProt
    Q92585
    Pathways
    Notch Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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