MAML1 Antikörper (AA 75-125)
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- Target Alle MAML1 Antikörper anzeigen
- MAML1 (Mastermind-Like 1 (MAML1))
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Bindungsspezifität
- AA 75-125
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MAML1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Verwendungszweck
- Rabbit anti-MAML1 Antibody, Affinity Purified
- Aufreinigung
- Affinity Purified
- Immunogen
- between AA 75 and 125
- Isotyp
- IgG
- Top Product
- Discover our top product MAML1 Primärantikörper
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- Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:25,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- MAML1 (Mastermind-Like 1 (MAML1))
- Andere Bezeichnung
- MAML1 (MAML1 Produkte)
- Synonyme
- mam1 antikoerper, mam-1 antikoerper, xmam1 antikoerper, MAML1 antikoerper, AI644666 antikoerper, AW743257 antikoerper, D930008C07Rik antikoerper, Mam-1 antikoerper, Mam1 antikoerper, mKIAA0200 antikoerper, mastermind like transcriptional coactivator 1 L homeolog antikoerper, mastermind like transcriptional coactivator 1 antikoerper, mastermind like 1 (Drosophila) antikoerper, mastermind-like transcriptional coactivator 1 antikoerper, maml1.L antikoerper, MAML1 antikoerper, Maml1 antikoerper
- Hintergrund
- Background: There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML1 is a critical coactivator for NOTCH signaling. MAML1 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors. MAML1 has been observed to interact with p300 to acetylate histones H3 and H4. MAML1 also interacts with p53 and functions independent of NOTCH signaling, as a coactivator of p53 target genes.
- Gen-ID
- 9794
- NCBI Accession
- NP_055572
- UniProt
- Q92585
- Pathways
- Notch Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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