F-Actin-Uncapping Protein LRRC16A (CARMIL1) (AA 1321-1371) Antikörper

Produktnummer ABIN7450068

Produktdetails

Target: F-Actin-Uncapping Protein LRRC16A (CARMIL1)

Bindungsspezifität: AA 1321-1371

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunoprecipitation (IP), Western Blotting (WB)

Verwendungszweck: Rabbit anti-CARMIL Antibody, Affinity Purified

Homologie: Mouse

Aufreinigung: Affinity Purified

Immunogen: Between AA 1321 and 1371

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Antigendetails

Target: F-Actin-Uncapping Protein LRRC16A (CARMIL1)

Andere Bezeichnung: CARMIL

Hintergrund: Background: CARMIL binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. It increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. CARMIL Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity).CARMIL may control actin dynamics in lamellipodi and be required for cell migration [taken from the Universal Protein Resource (UniProt) Q5VZK9].

Gen-ID: 55604

NCBI Accession: NP_060110

UniProt: Q5VZK9