RFWD2 Antikörper (AA 1-50)
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- Target Alle RFWD2 Antikörper anzeigen
- RFWD2 (Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2))
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Bindungsspezifität
- AA 1-50
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RFWD2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Verwendungszweck
- Rabbit anti-COP1/RFWD2 Antibody, Affinity Purified
- Aufreinigung
- Affinity Purified
- Immunogen
- Between AA 1 and 50
- Isotyp
- IgG
- Top Product
- Discover our top product RFWD2 Primärantikörper
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- Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- RFWD2 (Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2))
- Andere Bezeichnung
- COP1/RFWD2 (RFWD2 Produkte)
- Synonyme
- COP1 antikoerper, RNF200 antikoerper, AI316802 antikoerper, C80879 antikoerper, Cop1 antikoerper, RGD1304773 antikoerper, RFWD2 antikoerper, cop1 antikoerper, rnf200 antikoerper, zgc:163067 antikoerper, ring finger and WD repeat domain 2 antikoerper, ring finger and WD repeat domain 2, E3 ubiquitin protein ligase antikoerper, ring finger and WD repeat domain 2, E3 ubiquitin protein ligase L homeolog antikoerper, RFWD2 antikoerper, Rfwd2 antikoerper, rfwd2 antikoerper, rfwd2.L antikoerper
- Hintergrund
- Background: Constitutive photomorphogenic protein 1 (COP1) has been characterized in plants as a RING-finger-containing protein that functions to repress plant photomorphogenesis. In mammals, COP1 has been identified as an E3 ubiquitin ligase that negatively regulates p53 protein levels in unstressed cells. In response to DNA damage COP1 is phosphorylated by the ataxia telangiectasia mutated (ATM) protein kinase and is rapidly degraded releasing p53 to exert its tumor suppressor activities.
- Gen-ID
- 64326
- NCBI Accession
- NP_071902
- UniProt
- Q8NHY2
- Pathways
- Photoperiodism
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