EPC1 Antikörper (AA 325-375)

Produktnummer ABIN7450211

Produktdetails anti-EPC1 Antikörper

Target: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Bindungsspezifität: AA 325-375

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-EPC1 Antibody, Affinity Purified

Homologie: Mouse

Aufreinigung: Affinity Purified

Immunogen: between AA 325 and 375

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu EPC1

Target: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Andere Bezeichnung: EPC1 (EPC1 Produkte)

Synonyme: EPC1 antikoerper, Epl1 antikoerper, 2400007E14Rik antikoerper, 5730566F07Rik antikoerper, A930032N02Rik antikoerper, epc1 antikoerper, enhancer of polycomb homolog 1 antikoerper, enhancer of polycomb homolog 1 (Drosophila) a antikoerper, enhancer of polycomb homolog 1 (Drosophila) antikoerper, enhancer of polycomb homolog 1 L homeolog antikoerper, EPC1 antikoerper, epc1a antikoerper, Epc1 antikoerper, epc1 antikoerper, epc1.L antikoerper

Hintergrund: Background: Enhancer of polycomb homolog 1 (EPC1) is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage [taken from the Universal Protein Resource (UniProt) Q9H2F5].

Gen-ID: 80314

NCBI Accession: NP_079485

UniProt: Q9H2F5

Pathways: Regulation of Muscle Cell Differentiation