ERBB2IP Antikörper (AA 825-875)

Produktnummer ABIN7450219

Produktdetails anti-ERBB2IP Antikörper

Target: ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))

Bindungsspezifität: AA 825-875

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERBB2IP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-Erbin Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 825 and 875

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu ERBB2IP

Target: ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))

Andere Bezeichnung: Erbin (ERBB2IP Produkte)

Synonyme: ERBIN antikoerper, LAP2 antikoerper, ERBB2IP antikoerper, 1700028E05Rik antikoerper, Erbin antikoerper, mKIAA1225 antikoerper, Erbb2i antikoerper, Erbb2ip antikoerper, RGD1562952 antikoerper, erbb2ip antikoerper, zgc:152984 antikoerper, erbb2 interacting protein antikoerper, apurinic/apyrimidinic endodeoxyribonuclease 1 antikoerper, Erbb2 interacting protein antikoerper, ERBIN antikoerper, ERBB2IP antikoerper, erbin antikoerper, Erbin antikoerper

Hintergrund: Background: Erbin (Erbb2-interacting protein) is a member of the leucine-rich repeat and PDZ domain (LAP) family. Erbin contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction [taken from NCBI Entrez Gene (Gene ID: 55914)].

Gen-ID: 55914

UniProt: Q96RT1

Pathways: EGFR Signaling Pathway, Asymmetric Protein Localization