GCC2 Antikörper (AA 1-50)

Produktnummer ABIN7450275

Produktdetails anti-GCC2 Antikörper

Target: GCC2 (GRIP and Coiled-Coil Domain Containing 2 (GCC2))

Bindungsspezifität: AA 1-50

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-GCC185 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 1 and 50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu GCC2

Target: GCC2 (GRIP and Coiled-Coil Domain Containing 2 (GCC2))

Andere Bezeichnung: GCC185 (GCC2 Produkte)

Synonyme: GCC185 antikoerper, RANBP2L4 antikoerper, REN53 antikoerper, 0610043A03Rik antikoerper, 2210420P05Rik antikoerper, 2600014C01Rik antikoerper, AW112121 antikoerper, mKIAA0336 antikoerper, Lims1 antikoerper, GRIP and coiled-coil domain containing 2 antikoerper, GCC2 antikoerper, gcc2 antikoerper, Gcc2 antikoerper

Hintergrund: Background: 185 kDa Golgi coiled-coil protein (GCC85) is a Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector, GCC85 is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. Golgin may also play a role in transport between the recycling endosomes and the Golgi. It is required for maintenance of the Golgi structure, and it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2. RanBP2L4, renal carcinoma antigen NY-REN-53, and KIAA0336 [taken from the Universal Protein Resource (UniProt) Q81WJ2].

Gen-ID: 9648

NCBI Accession: NP_852118

UniProt: Q8IWJ2

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interaktom