ZBTB33 Antikörper (AA 622-672)
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- Target Alle ZBTB33 Antikörper anzeigen
- ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))
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Bindungsspezifität
- AA 622-672
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZBTB33 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Verwendungszweck
- Rabbit anti-Kaiso Antibody, Affinity Purified
- Homologie
- Mouse
- Aufreinigung
- Affinity Purified
- Immunogen
- between AA 622 and 672
- Isotyp
- IgG
- Top Product
- Discover our top product ZBTB33 Primärantikörper
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- Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))
- Andere Bezeichnung
- Kaiso (ZBTB33 Produkte)
- Synonyme
- kaiso antikoerper, ZNF-kaiso antikoerper, ZNF348 antikoerper, AW260253 antikoerper, E130014G12Rik antikoerper, Kaiso antikoerper, Znf-kaiso antikoerper, RGD1566309 antikoerper, zinc finger and BTB domain containing 33 S homeolog antikoerper, zinc finger and BTB domain containing 33 antikoerper, zbtb33.S antikoerper, ZBTB33 antikoerper, Zbtb33 antikoerper
- Hintergrund
- Background: Transcriptional regulator Kaiso possesses bimodal DNA-binding specificity and binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. Kaiso contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. Kaiso may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. [taken from NCBI Entrez Gene (Gene ID: 10009)].
- Gen-ID
- 10009
- NCBI Accession
- NP_006768
- UniProt
- Q86T24
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