LIN54 Antikörper (AA 1-50)
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- Target Alle LIN54 Antikörper anzeigen
- LIN54 (Lin-54 Homolog (LIN54))
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Bindungsspezifität
- AA 1-50
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LIN54 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Verwendungszweck
- Rabbit anti-LIN54 Antibody, Affinity Purified
- Aufreinigung
- Affinity Purified
- Immunogen
- Between AA 1 and 50
- Isotyp
- IgG
- Top Product
- Discover our top product LIN54 Primärantikörper
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- Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- LIN54 (Lin-54 Homolog (LIN54))
- Andere Bezeichnung
- LIN54 (LIN54 Produkte)
- Synonyme
- CXCDC1 antikoerper, JC8.6 antikoerper, MIP120 antikoerper, 4832414L08 antikoerper, AI461788 antikoerper, mKIAA2037 antikoerper, RGD1311361 antikoerper, lin-54 DREAM MuvB core complex component antikoerper, lin-54 homolog (C. elegans) antikoerper, LIN54 antikoerper, Lin54 antikoerper
- Hintergrund
- Background: LIN54 is a component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes. In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation. In the complex, LIN54 acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner [taken from the Universal Protein Resource (UniProt) Q6MZP7].
- Gen-ID
- 132660
- NCBI Accession
- NP_919258
- UniProt
- Q6MZP7
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
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