MPRIP Antikörper (AA 550-600)

Produktnummer ABIN7450461

Produktdetails anti-MPRIP Antikörper

Target: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Bindungsspezifität: AA 550-600

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MPRIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-MPRIP/M-RIP Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 550 and 600

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu MPRIP

Target: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Andere Bezeichnung: MPRIP/M-RIP (MPRIP Produkte)

Synonyme: M-RIP antikoerper, MRIP antikoerper, RHOIP3 antikoerper, RIP3 antikoerper, p116Rip antikoerper, 9530046C02 antikoerper, AA536749 antikoerper, AI647711 antikoerper, C76423 antikoerper, Rhoip3 antikoerper, mKIAA0864 antikoerper, M-rip antikoerper, Mrip antikoerper, myosin phosphatase Rho interacting protein antikoerper, MPRIP antikoerper, Mprip antikoerper

Hintergrund: Background: MPRIP targets myosin phosphatase to the actin cytoskeleton. It is required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MPRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells [taken from the Universal Protein Resource (UniProt) Q6WCQ1].

Gen-ID: 23164

UniProt: Q6WCQ1