POLR3E Antikörper (AA 475-525)

Produktnummer ABIN7450584

Produktdetails anti-POLR3E Antikörper

Target: POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))

Bindungsspezifität: AA 475-525

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR3E Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-POLR3E Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 475 and 525

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu POLR3E

Target: POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))

Andere Bezeichnung: POLR3E (POLR3E Produkte)

Hintergrund: Background: POLR3E (RNA polymerase III polypeptide E 80 kDa) is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3E is a specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. POLR3E plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses [taken from the Universal Protein Resource (UniProt) Q9NVU0].

Gen-ID: 55718

NCBI Accession: NP_060589

UniProt: Q9NVU0