MPRIP Antikörper (AA 400-450)
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- Target Alle MPRIP Antikörper anzeigen
- MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))
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Bindungsspezifität
- AA 400-450
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MPRIP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Verwendungszweck
- Rabbit anti-RIP3 Antibody, Affinity Purified
- Aufreinigung
- Affinity Purified
- Immunogen
- Between AA 400 and 450
- Isotyp
- IgG
- Top Product
- Discover our top product MPRIP Primärantikörper
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- Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))
- Andere Bezeichnung
- RIP3 (MPRIP Produkte)
- Synonyme
- M-RIP antikoerper, MRIP antikoerper, RHOIP3 antikoerper, RIP3 antikoerper, p116Rip antikoerper, 9530046C02 antikoerper, AA536749 antikoerper, AI647711 antikoerper, C76423 antikoerper, Rhoip3 antikoerper, mKIAA0864 antikoerper, M-rip antikoerper, Mrip antikoerper, myosin phosphatase Rho interacting protein antikoerper, MPRIP antikoerper, Mprip antikoerper
- Hintergrund
- Background: Receptor-interacting serine/threonine-protein kinase 3 (RIP3) is essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIP3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIP3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production [taken from the Universal Protein Resource (UniProt) Q9Y572].
- Gen-ID
- 11035
- NCBI Accession
- NP_006862
- UniProt
- Q9Y572
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