SOS2 Antikörper (AA 1282-1332)

Produktnummer ABIN7450757

Produktdetails anti-SOS2 Antikörper

Target: SOS2 (Son of Sevenless Homolog 2 (SOS2))

Bindungsspezifität: AA 1282-1332

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-SOS2 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 1282 and 1332

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu SOS2

Target: SOS2 (Son of Sevenless Homolog 2 (SOS2))

Andere Bezeichnung: SOS2 (SOS2 Produkte)

Synonyme: Sos1 antikoerper, SOS-2 antikoerper, mSOS-2 antikoerper, SOS Ras/Rho guanine nucleotide exchange factor 2 antikoerper, son of sevenless homolog 2 (Drosophila) antikoerper, Sos2 antikoerper, SOS2 antikoerper

Hintergrund: Background: SOS2 (son of sevenless homolog 2) is a human paralog of the Drosophila SOS gene. Drosophila SOS was originally identified as a gene that functioned downstream of the sevenless gene in the Ras/MAP kinase signaling pathway. SOS and its paralogs, SOS1 and SOS2, function as guanine nucleotide exchange factors that act on Ras-GTPases to cause release of GDP in exchange for GTP. Although targeted disruption of SOS1 results in embryonic lethality, disruption of SOS2 does not have any effects on mouse development, growth, or fertility.

Gen-ID: 6655

NCBI Accession: NP_008870

UniProt: Q07890

Pathways: RTK Signalweg, Neurotrophin Signalübertragung, Hepatitis C, BCR Signaling