SPG20 Antikörper (AA 350-400)

Produktnummer ABIN7450761

Produktdetails anti-SPG20 Antikörper

Target: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Bindungsspezifität: AA 350-400

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPG20 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-SPG20 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 350 and 400

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu SPG20

Target: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Andere Bezeichnung: SPG20 (SPG20 Produkte)

Synonyme: SPARTIN antikoerper, TAHCCP1 antikoerper, AI840044 antikoerper, C79168 antikoerper, mKIAA0610 antikoerper, spartin antikoerper, Spg20 antikoerper, spg20a antikoerper, zgc:172059 antikoerper, spg20b antikoerper, zgc:153766 antikoerper, spartin antikoerper, spastic paraplegia 20, spartin (Troyer syndrome) homolog (human) antikoerper, spartin a antikoerper, spartin b antikoerper, SPART antikoerper, Spg20 antikoerper, Spart antikoerper, sparta antikoerper, spartb antikoerper

Hintergrund: Background: Spastic paraplegia 20 protein (SPG20) is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Mutations associated with the SPG20 gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome) [taken from NCBI Entrez Gene (Gene ID: 23111)].

Gen-ID: 23111

UniProt: Q8N0X7

Pathways: Regulation of Cell Size, SARS-CoV-2 Protein Interaktom