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Strumpellin Antikörper (AA 1109-1159)

WASHC5 Reaktivität: Human, Maus WB, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7450762
  • Target Alle Strumpellin (WASHC5) Antikörper anzeigen
    Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))
    Bindungsspezifität
    • 3
    • 1
    • 1
    AA 1109-1159
    Reaktivität
    • 4
    • 3
    • 2
    Human, Maus
    Wirt
    • 5
    Kaninchen
    Klonalität
    • 5
    Polyklonal
    Konjugat
    • 5
    Dieser Strumpellin Antikörper ist unkonjugiert
    Applikation
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Verwendungszweck
    Rabbit anti-SPG8/Strumpellin Antibody, Affinity Purified
    Homologie
    Zebrafish,Orangutan
    Aufreinigung
    Affinity Purified
    Immunogen
    Between AA 1109 and 1159
    Isotyp
    IgG
    Top Product
    Discover our top product WASHC5 Primärantikörper
  • Applikationshinweise

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))
    Andere Bezeichnung
    SPG8/Strumpellin (WASHC5 Produkte)
    Synonyme
    SPG8 antikoerper, AL022848 antikoerper, C76463 antikoerper, Kiaa0196 antikoerper, mKIAA0196 antikoerper, strumpellin antikoerper, WASH complex subunit 5 antikoerper, WASHC5 antikoerper, washc5 antikoerper, Washc5 antikoerper
    Hintergrund
    Background: SPG8/Strumpellin acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093). SPG8/Strumpellin may be involved in axonal outgrowth [taken from the Universal Protein Resource (UniProt) Q12768].
    Gen-ID
    9897
    UniProt
    Q12768
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