Strumpellin Antikörper (AA 1109-1159)

Produktnummer ABIN7450762

Produktdetails anti-Strumpellin Antikörper

Target: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Bindungsspezifität: AA 1109-1159

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Strumpellin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-SPG8/Strumpellin Antibody, Affinity Purified

Homologie: Zebrafish,Orangutan

Aufreinigung: Affinity Purified

Immunogen: Between AA 1109 and 1159

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Strumpellin

Target: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Andere Bezeichnung: SPG8/Strumpellin (WASHC5 Produkte)

Synonyme: SPG8 antikoerper, AL022848 antikoerper, C76463 antikoerper, Kiaa0196 antikoerper, mKIAA0196 antikoerper, strumpellin antikoerper, WASH complex subunit 5 antikoerper, WASHC5 antikoerper, washc5 antikoerper, Washc5 antikoerper

Hintergrund: Background: SPG8/Strumpellin acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093). SPG8/Strumpellin may be involved in axonal outgrowth [taken from the Universal Protein Resource (UniProt) Q12768].

Gen-ID: 9897

UniProt: Q12768