VTA1 Antikörper (AA 250-300)
Kurzübersicht für VTA1 Antikörper (AA 250-300) (ABIN7450903)
Target
Alle VTA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 250-300
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Verwendungszweck
- Rabbit anti-VTA1/LIP5 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 250 and 300
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- VTA1 (Vps20-Associated 1 Homolog (VTA1))
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Andere Bezeichnung
- VTA1/LIP5
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Hintergrund
- Background: VTA1 is involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. VTA1 is thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. It is involved in the sorting and down-regulation of EGFR (By similarity) [taken from the Universal Protein Resource (UniProt) Q9NP79].
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Gen-ID
- 51534
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UniProt
- Q9NP79
Target
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