VTA1 Antikörper (AA 250-300)

Produktnummer ABIN7450903

Produktdetails anti-VTA1 Antikörper

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Bindungsspezifität: AA 250-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VTA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-VTA1/LIP5 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 250 and 300

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu VTA1

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Andere Bezeichnung: VTA1/LIP5 (VTA1 Produkte)

Hintergrund: Background: VTA1 is involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. VTA1 is thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. It is involved in the sorting and down-regulation of EGFR (By similarity) [taken from the Universal Protein Resource (UniProt) Q9NP79].

Gen-ID: 51534

UniProt: Q9NP79