NSMCE2 Antikörper (AA 197-247)

Produktnummer ABIN7451060

Produktdetails anti-NSMCE2 Antikörper

Target: NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Bindungsspezifität: AA 197-247

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NSMCE2 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-MMS21 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 197 and 247

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451060 has not performed satisfactorily when used for WB of MMS21 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MMS21.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu NSMCE2

Target: NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Andere Bezeichnung: MMS21 (NSMCE2 Produkte)

Synonyme: 1110014D18Rik antikoerper, AI661537 antikoerper, RGD1305156 antikoerper, C8orf36 antikoerper, MMS21 antikoerper, NSE2 antikoerper, ZMIZ7 antikoerper, Non-SMC element 2 antikoerper, NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase antikoerper, NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog antikoerper, Smc5-6 complex non-SMC subunit 2 antikoerper, Nsmce2 antikoerper, NSMCE2 antikoerper, nsmce2.L antikoerper, nse2 antikoerper

Hintergrund: Background: The human MMS21 (Methyl Methanesulfonate-Sensitivity protein 21) homolog is also known as E3 SUMO-protein ligase NSE2. MMS21 is an E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand break repair by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks [taken from the Universal Protein Resource (UniProt) Q96MF7].

Gen-ID: 286053

NCBI Accession: NP_775956

UniProt: Q96MF7