LZTS2 Antikörper (C-Term)

Produktnummer ABIN7451099

Produktdetails anti-LZTS2 Antikörper

Target: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LZTS2 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-LZTS2 Antibody, Affinity Purified

Homologie: Mouse,Rat,Bovine

Aufreinigung: Affinity Purified

Immunogen: Between AA 660 and C-term

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451099 has not performed satisfactorily when used for WB of LZTS2 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of LZTS2.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu LZTS2

Target: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Andere Bezeichnung: LZTS2 (LZTS2 Produkte)

Synonyme: lapser1 antikoerper, MGC89253 antikoerper, si:dkey-250a11.1 antikoerper, LAPSER1 antikoerper, BC014695 antikoerper, mKIAA1813 antikoerper, Lapser1 antikoerper, leucine zipper, putative tumor suppressor 2 antikoerper, leucine zipper tumor suppressor 2 antikoerper, leucine zipper, putative tumor suppressor 2a antikoerper, leucine zipper, putative tumor suppressor 2 S homeolog antikoerper, lzts2 antikoerper, LZTS2 antikoerper, lzts2a antikoerper, Lzts2 antikoerper, lzts2.S antikoerper

Hintergrund: Background: leucine zipper, putative tumor suppressor 2 (LZTS2) is az negative regulator of katanin-mediated microtubule severing and release from the centrosome. It is required for central spindle formation and the completion of cytokinesis. LZTS2 may negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. It is a negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin  [taken from the Universal Protein Resource (UniProt) Q9BRK4].

Gen-ID: 84445

UniProt: Q9BRK4