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MTMR6 Antikörper (AA 571-621)

MTMR6 Reaktivität: Human IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7451181
  • Target Alle MTMR6 Antikörper anzeigen
    MTMR6 (Myotubularin Related Protein 6 (MTMR6))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    AA 571-621
    Reaktivität
    • 30
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 28
    • 2
    Kaninchen
    Klonalität
    • 30
    Polyklonal
    Konjugat
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser MTMR6 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 18
    • 2
    • 1
    Immunoprecipitation (IP)
    Verwendungszweck
    Rabbit anti-MTMR6 Antibody, Affinity Purified
    Aufreinigung
    Affinity Purified
    Immunogen
    Between AA 571 and 621
    Isotyp
    IgG
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  • Applikationshinweise

    IP: 2 - 10 μg/mg lysate

    WB: Not recommended. ABIN7451181 has not performed satisfactorily when used for WB of MTMR6 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MTMR6.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    MTMR6 (Myotubularin Related Protein 6 (MTMR6))
    Andere Bezeichnung
    MTMR6 (MTMR6 Produkte)
    Synonyme
    4022440C11Rik antikoerper, AI428804 antikoerper, AU041072 antikoerper, zgc:55289 antikoerper, wu:fi04a11 antikoerper, si:dkey-286f3.1 antikoerper, zgc:56405 antikoerper, myotubularin related protein 6 antikoerper, myotubularin related protein 8 antikoerper, MTMR6 antikoerper, Mtmr6 antikoerper, mtmr6 antikoerper, mtmr8 antikoerper
    Hintergrund
    Background: Myotubularin-related protein 6 (MTMR6) is a phosphatase that acts on lipids with a phosphoinositol headgroup. MTMR6 acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells [taken from the Universal Protein Resource (UniProt) Q9Y217].
    Gen-ID
    9107
    UniProt
    Q9Y217
    Pathways
    Inositol Metabolic Process
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