IGKV1-27 Antikörper (AA 525-575)

Produktnummer ABIN7451604

Produktdetails anti-IGKV1-27 Antikörper

Target: IGKV1-27 (Immunoglobulin kappa Variable 1-27 (IGKV1-27))

Bindungsspezifität: AA 525-575

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGKV1-27 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-A20 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 525 and 575

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu IGKV1-27

Target: IGKV1-27 (Immunoglobulin kappa Variable 1-27 (IGKV1-27))

Andere Bezeichnung: A20 (IGKV1-27 Produkte)

Synonyme: A20 antikoerper, OTUD7C antikoerper, TNFA1P2 antikoerper, TNF alpha induced protein 3 antikoerper, TNFAIP3 antikoerper

Hintergrund: Background: Zinc-finger protein A20 was identified as a transcript that was rapidly induced by tumor-necrosis factor alpha (TNF-alpha). A20 is an essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Upon TNF stimulation, A20 deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains [taken from the Universal Protein Resource (UniProt) P21580].

Gen-ID: 7128

NCBI Accession: NP_006281

UniProt: P21580

Pathways: Activation of Innate immune Response