ASXL2 Antikörper (AA 600-650)

Produktnummer ABIN7451647

Produktdetails anti-ASXL2 Antikörper

Target: ASXL2 (Additional Sex Combs Like 2 (ASXL2))

Bindungsspezifität: AA 600-650

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASXL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-ASXL2 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 600 and 650

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu ASXL2

Target: ASXL2 (Additional Sex Combs Like 2 (ASXL2))

Andere Bezeichnung: ASXL2 (ASXL2 Produkte)

Synonyme: asxh2 antikoerper, ASXH2 antikoerper, 4930556B16Rik antikoerper, mKIAA1685 antikoerper, additional sex combs like 2, transcriptional regulator antikoerper, additional sex combs like 2 (Drosophila) antikoerper, Asxl2 antikoerper, ASXL2 antikoerper, asxl2 antikoerper

Hintergrund: Background: The gene that encodes Additional sex combs-like protein 2 (ASXL2) is a homolog of the drosophila additional sex combs (Asx) gene. Drosophila Asx is in a class of proteins known as ETP (enhancers of trithorax and polycomb). ETP proteins regulate polycomb-group (PcG) and trithorax-group (trxG) proteins which function to modify the methylation of histones and structure of chromatin. Mutations in ASXL1 are implicated in the development of myelodysplastic syndromes (MDS), a group of hematological diseases characterized by ineffective hematopoiesis and a predisposition to acute myeloid leukemia (AML).

Gen-ID: 55252

NCBI Accession: NP_060733

UniProt: Q76L83

Pathways: Positive Regulation of fat Cell Differentiation