BRAP Antikörper (AA 560-592)
-
- Target Alle BRAP Antikörper anzeigen
- BRAP (BRCA1 Associated Protein (BRAP))
-
Bindungsspezifität
- AA 560-592
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser BRAP Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Verwendungszweck
- Rabbit anti-BRAP Antibody, Affinity Purified
- Aufreinigung
- Affinity Purified
- Immunogen
- between AA 560 and 592
- Isotyp
- IgG
- Top Product
- Discover our top product BRAP Primärantikörper
-
-
- Applikationshinweise
-
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
-
- Target
- BRAP (BRCA1 Associated Protein (BRAP))
- Andere Bezeichnung
- BRAP (BRAP Produkte)
- Synonyme
- imp antikoerper, MGC68778 antikoerper, zgc:92894 antikoerper, BRAP antikoerper, BRAP2 antikoerper, IMP antikoerper, RNF52 antikoerper, 3010002G07Rik antikoerper, BRCA1 associated protein S homeolog antikoerper, BRCA1 associated protein antikoerper, BRCA1-associated protein antikoerper, brca1-associated protein antikoerper, brap.S antikoerper, brap antikoerper, BRAP antikoerper, NAEGRDRAFT_81654 antikoerper, CC1G_00971 antikoerper, CpipJ_CPIJ003557 antikoerper, Tsp_05101 antikoerper, LOC100282389 antikoerper, Brap antikoerper
- Hintergrund
- Background: BRCA1-associated protein (BRAP) negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. BRAP acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. BRAP may also act as a cytoplasmic retention protein with a role in regulating nuclear transport [taken from the Universal Protein Resource (UniProt) Q7Z569].
- Gen-ID
- 8315
- NCBI Accession
- NP_006759
- UniProt
- Q7Z569
-