GEMIN5 Antikörper (AA 1360-1410)

Produktnummer ABIN7451794

Produktdetails anti-GEMIN5 Antikörper

Target: GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))

Bindungsspezifität: AA 1360-1410

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GEMIN5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-Gemin5 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 1360 and 1410

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu GEMIN5

Target: GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))

Andere Bezeichnung: Gemin5 (GEMIN5 Produkte)

Synonyme: GEMIN-5 antikoerper, AA407055 antikoerper, AA407208 antikoerper, AI451603 antikoerper, BB194447 antikoerper, C330013N08 antikoerper, gem nuclear organelle associated protein 5 antikoerper, gem (nuclear organelle) associated protein 5 antikoerper, GEMIN5 antikoerper, Gemin5 antikoerper

Hintergrund: Background: Gemin5 is a component of the SMN (survival of motor neurons) complex. The SMN complex is composed of the SMN protein and several Gemins (2-7) and is involved in the assembly of snRNPs in the cytoplasm and their transport to the nucleus. The SMN complex localizes to nuclear focal structures called gems or Gemini of coiled bodies. Gemin 5 has been shown to be responsible for recognizing and binding the snRNP code during snRNP biogenesis. Recent studies have shown that Gemin 5 is rarely detectable in SMN complexes associated with gems/Cajal bodies in the nucleus and may play a specific role in cytoplasmic SMN complexes. It has also been shown to function as a scaffold protein for ASK1-JNK1 signaling.

Gen-ID: 25929

NCBI Accession: NP_056280

UniProt: Q8TEQ6

Pathways: Ribonucleoprotein Complex Subunit Organization