TOM1 Antikörper (AA 450-492)

Produktnummer ABIN7452105

Produktdetails anti-TOM1 Antikörper

Target: TOM1 (Target of Myb 1 (TOM1))

Bindungsspezifität: AA 450-492

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-TOM1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 450 and 492

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu TOM1

Target: TOM1 (Target of Myb 1 (TOM1))

Andere Bezeichnung: TOM1 (TOM1 Produkte)

Synonyme: TOM-1B antikoerper, tom-1A antikoerper, target of myb1 membrane trafficking protein antikoerper, target of myb1 trafficking protein antikoerper, TOM1 antikoerper, Tom1 antikoerper

Hintergrund: Background: TOM1 (target of myb1) was originally identified as a gene activated by the expression of oncogenic Myb1. TOM1 has been shown to form a complex with tollip (toll-interacting protein) and to bind ubiquitin chains. It has also been shown to bind to clathrin heavy chain and is proposed to function to link polyubiquitinated proteins to clathrin and regulate endosomal trafficking of ubiquitinated proteins. Recent evidence shows that TOM1 bridges endofin to clathrin and is critical for the endosomal targeting of clathrin by endofin.

Gen-ID: 10043

NCBI Accession: NP_005479

UniProt: O60784