SPEN Antikörper (AA 3375-3425)
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- Target Alle SPEN Antikörper anzeigen
- SPEN (Spen Homolog, Transcriptional Regulator (SPEN))
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Bindungsspezifität
- AA 3375-3425
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SPEN Antikörper ist unkonjugiert
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Applikation
- Immunoprecipitation (IP)
- Verwendungszweck
- Rabbit anti-SHARP Antibody, Affinity Purified
- Aufreinigung
- Affinity Purified
- Immunogen
- between AA 3375 and 3425
- Isotyp
- IgG
- Top Product
- Discover our top product SPEN Primärantikörper
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- Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. ABIN7451040 can be used successfully for WB of enriched preparations (e.g. immunoprecipitated) SHARP.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- SPEN (Spen Homolog, Transcriptional Regulator (SPEN))
- Andere Bezeichnung
- SHARP (SPEN Produkte)
- Synonyme
- HIAA0929 antikoerper, MINT antikoerper, RBM15C antikoerper, SHARP antikoerper, Mint antikoerper, mKIAA0929 antikoerper, spen family transcriptional repressor antikoerper, SPEN homolog, transcriptional regulator (Drosophila) antikoerper, SPEN antikoerper, Spen antikoerper
- Hintergrund
- Background: SHARP functions as a transcriptional repressor by interacting with proteins involved in deacetylation such as the NuRD (nucleosome remodeling) complex. SHARP can also repress transcription by interacting with corepressors such as SMRT/NCoR (silencing mediator for retinoid and thyroid receptors/nuclear receptor corepressor). SHARP is able to suppress transcription through the Notch/RBP-J signaling pathway by competing RBP-J binding with the intracellular domain of Notch.
- Gen-ID
- 23013
- NCBI Accession
- NP_055816
- UniProt
- Q96T58
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