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SPEN Antikörper (AA 3375-3425)

SPEN Reaktivität: Human IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7452220
  • Target Alle SPEN Antikörper anzeigen
    SPEN (Spen Homolog, Transcriptional Regulator (SPEN))
    Bindungsspezifität
    • 2
    • 1
    • 1
    AA 3375-3425
    Reaktivität
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 4
    • 1
    Kaninchen
    Klonalität
    • 5
    Polyklonal
    Konjugat
    • 5
    Dieser SPEN Antikörper ist unkonjugiert
    Applikation
    • 3
    • 2
    Immunoprecipitation (IP)
    Verwendungszweck
    Rabbit anti-SHARP Antibody, Affinity Purified
    Aufreinigung
    Affinity Purified
    Immunogen
    between AA 3375 and 3425
    Isotyp
    IgG
    Top Product
    Discover our top product SPEN Primärantikörper
  • Applikationshinweise

    IP: 2 - 5 μg/mg lysate

    WB: Not recommended. ABIN7451040 can be used successfully for WB of enriched preparations (e.g. immunoprecipitated) SHARP.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    SPEN (Spen Homolog, Transcriptional Regulator (SPEN))
    Andere Bezeichnung
    SHARP (SPEN Produkte)
    Synonyme
    HIAA0929 antikoerper, MINT antikoerper, RBM15C antikoerper, SHARP antikoerper, Mint antikoerper, mKIAA0929 antikoerper, spen family transcriptional repressor antikoerper, SPEN homolog, transcriptional regulator (Drosophila) antikoerper, SPEN antikoerper, Spen antikoerper
    Hintergrund
    Background: SHARP functions as a transcriptional repressor by interacting with proteins involved in deacetylation such as the NuRD (nucleosome remodeling) complex. SHARP can also repress transcription by interacting with corepressors such as SMRT/NCoR (silencing mediator for retinoid and thyroid receptors/nuclear receptor corepressor). SHARP is able to suppress transcription through the Notch/RBP-J signaling pathway by competing RBP-J binding with the intracellular domain of Notch.
    Gen-ID
    23013
    NCBI Accession
    NP_055816
    UniProt
    Q96T58
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