WWP1 Antikörper (AA 300-350)

Produktnummer ABIN7452554

Produktdetails anti-WWP1 Antikörper

Target: WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

Bindungsspezifität: AA 300-350

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WWP1 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-WWP1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 300 and 350

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: Not recommended

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu WWP1

Target: WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

Andere Bezeichnung: WWP1 (WWP1 Produkte)

Synonyme: AIP5 antikoerper, Tiul1 antikoerper, hSDRP1 antikoerper, 8030445B08Rik antikoerper, SDRP1 antikoerper, WWP1 antikoerper, aip5 antikoerper, tiul1 antikoerper, hsdrp1 antikoerper, WW domain containing E3 ubiquitin protein ligase 1 antikoerper, WWP1 antikoerper, Wwp1 antikoerper, wwp1 antikoerper

Hintergrund: Background: WW domain-containing protein 1 (WWP1) functions as an E3 ubiquitin-protein ligase. WWP1 ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. WWP1 also ubiquitinates and promotes degradation of TGFBR1, TGFBR1 ubiquitination is enhanced by SMAD7, and WWP1 also ubiquitinates SMAD7 as well as SMAD6. [taken from the Universal Protein Resource (UniProt) Q9H0M0].

Gen-ID: 11059

NCBI Accession: NP_008944

UniProt: Q9H0M0