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DUSP12 Antikörper (AA 1-50)

DUSP12 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7452603
  • Target Alle DUSP12 Antikörper anzeigen
    DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
    Bindungsspezifität
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-50
    Reaktivität
    • 30
    • 13
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 27
    • 3
    Kaninchen
    Klonalität
    • 30
    Polyklonal
    Konjugat
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DUSP12 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 11
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Verwendungszweck
    Rabbit anti-DUSP12 Antibody, Affinity Purified
    Aufreinigung
    Affinity Purified
    Immunogen
    Between AA 1 and 50
    Isotyp
    IgG
    Top Product
    Discover our top product DUSP12 Primärantikörper
  • Applikationshinweise

    IP: 20 μL/mg lysate

    WB: 1:2,000 - 1:10,000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
    Andere Bezeichnung
    DUSP12 (DUSP12 Produkte)
    Hintergrund
    Background: Dual specificity protein phosphatase 12 (DUSP12) is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP12 is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain [taken from NCBI Entrez Gene (Gene ID: 11266)].
    Gen-ID
    11266
    UniProt
    Q9UNI6
    Pathways
    Regulation of Carbohydrate Metabolic Process
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