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SMCP Antikörper (AA 575-625)

SMCP Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7452707
  • Target Alle SMCP Antikörper anzeigen
    SMCP (Sperm Mitochondria Associated Cysteine Rich Protein (SMCP))
    Bindungsspezifität
    • 9
    • 8
    • 8
    • 7
    AA 575-625
    Reaktivität
    Human
    Wirt
    • 29
    • 13
    Kaninchen
    Klonalität
    • 29
    • 13
    Polyklonal
    Konjugat
    • 12
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser SMCP Antikörper ist unkonjugiert
    Applikation
    • 23
    • 22
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Verwendungszweck
    Rabbit anti-MCSP Antibody, Affinity Purified
    Aufreinigung
    Affinity Purified
    Immunogen
    between AA 575 and 625
    Isotyp
    IgG
    Top Product
    Discover our top product SMCP Primärantikörper
  • Applikationshinweise

    IP: 5 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    SMCP (Sperm Mitochondria Associated Cysteine Rich Protein (SMCP))
    Andere Bezeichnung
    MCSP (SMCP Produkte)
    Synonyme
    HSMCSGEN1 antikoerper, MCS antikoerper, MCSP antikoerper, Mcs antikoerper, Mcsp antikoerper, sperm mitochondria associated cysteine rich protein antikoerper, sperm mitochondria-associated cysteine-rich protein antikoerper, SMCP antikoerper, Smcp antikoerper
    Hintergrund
    Background: Melanoma chondroitin sulfate proteoglycan (MCSP) is a cell-surface antigen expressed early in melanoma progression. It has been found to be involved in the spreading, invasion, and migration of human melanoma. MCSP influences melanoma behavior via the activation of the Cdc42 GTPase and phosphorylation of p130Cas. MCSP also activates signaling cascades involving FAK and ERK1/ERK2. In addition to its expression in melanoma cells, MCSP is also found in breast carcinomas, gliomas, neuroblastomas, and acute leukemias. MCSP is being considered as a target antigen for cancer immunotherapy.
    Gen-ID
    1464
    NCBI Accession
    NP_001888
    UniProt
    Q6UVK1
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