SMCP Antikörper (AA 575-625)
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- Target Alle SMCP Antikörper anzeigen
- SMCP (Sperm Mitochondria Associated Cysteine Rich Protein (SMCP))
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Bindungsspezifität
- AA 575-625
- Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SMCP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Verwendungszweck
- Rabbit anti-MCSP Antibody, Affinity Purified
- Aufreinigung
- Affinity Purified
- Immunogen
- between AA 575 and 625
- Isotyp
- IgG
- Top Product
- Discover our top product SMCP Primärantikörper
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- Applikationshinweise
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IP: 5 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- SMCP (Sperm Mitochondria Associated Cysteine Rich Protein (SMCP))
- Andere Bezeichnung
- MCSP (SMCP Produkte)
- Synonyme
- HSMCSGEN1 antikoerper, MCS antikoerper, MCSP antikoerper, Mcs antikoerper, Mcsp antikoerper, sperm mitochondria associated cysteine rich protein antikoerper, sperm mitochondria-associated cysteine-rich protein antikoerper, SMCP antikoerper, Smcp antikoerper
- Hintergrund
- Background: Melanoma chondroitin sulfate proteoglycan (MCSP) is a cell-surface antigen expressed early in melanoma progression. It has been found to be involved in the spreading, invasion, and migration of human melanoma. MCSP influences melanoma behavior via the activation of the Cdc42 GTPase and phosphorylation of p130Cas. MCSP also activates signaling cascades involving FAK and ERK1/ERK2. In addition to its expression in melanoma cells, MCSP is also found in breast carcinomas, gliomas, neuroblastomas, and acute leukemias. MCSP is being considered as a target antigen for cancer immunotherapy.
- Gen-ID
- 1464
- NCBI Accession
- NP_001888
- UniProt
- Q6UVK1
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