POLA2 Antikörper (AA 448-498)

Produktnummer ABIN7452745

Produktdetails anti-POLA2 Antikörper

Target: POLA2 (Polymerase (DNA Directed), alpha 2 (70kD Subunit) (POLA2))

Bindungsspezifität: AA 448-498

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-PolA2 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 448 and 498

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 5 - 15 μg/mg lysate

WB: 1:1,000 - 1:5,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu POLA2

Target: POLA2 (Polymerase (DNA Directed), alpha 2 (70kD Subunit) (POLA2))

Andere Bezeichnung: PolA2 (POLA2 Produkte)

Synonyme: DNA polymerase alpha 2 antikoerper, F12B7.19 antikoerper, F12B7_19 antikoerper, zgc:56124 antikoerper, zgc:77841 antikoerper, wu:fb48f05 antikoerper, AI573378 antikoerper, DNA polymerase alpha 2, accessory subunit antikoerper, DNA polymerase alpha 2 antikoerper, polymerase (DNA directed), alpha 2 antikoerper, polymerase (DNA directed), alpha 2, accessory subunit L homeolog antikoerper, polymerase (DNA directed), alpha 2, accessory subunit antikoerper, POLA2 antikoerper, pola2 antikoerper, pola2.L antikoerper, Pola2 antikoerper

Hintergrund: Background: DNA polymerase alpha is a four-subunit enzyme that exhibits DNA polymerase and primase activity. The four subunits of the heterotetrameric DNA pol alpha are A, B, C, and D. Subunit A displays the catalytic activity while the C and D subunits exhibit the primase activity. DNA polymerase (pol) alpha subunit B (PolA2) is the 70 kDa subunit that may serve to couple the DNA pol alpha-primase complex to the initiation/elongation machinery. DNA pol alpha is the only polymerase in eukaryotic cells that is capable of starting chains de novo.

Gen-ID: 23649

NCBI Accession: NP_002680

UniProt: Q14181

Pathways: Telomere Maintenance, Mitotic G1-G1/S Phases, DNA Replication, Protein targeting to Nucleus, Synthesis of DNA, SARS-CoV-2 Protein Interaktom