ZNF207 Antikörper (AA 428-478)

Produktnummer ABIN7452845

Produktdetails anti-ZNF207 Antikörper

Target: ZNF207 (Zinc Finger Protein 207 (ZNF207))

Bindungsspezifität: AA 428-478

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF207 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-ZNF207 Antibody, Affinity Purified

Homologie: Orangutan

Aufreinigung: Affinity Purified

Immunogen: between AA 428 and 478

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 50-100 μL/mg lysate

WB: 1:10,000 - 1:25,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu ZNF207

Target: ZNF207 (Zinc Finger Protein 207 (ZNF207))

Andere Bezeichnung: ZNF207 (ZNF207 Produkte)

Synonyme: MGC116398 antikoerper, 4m77 antikoerper, MGC75627 antikoerper, ZNF207 antikoerper, Zfp207 antikoerper, wu:fb50g07 antikoerper, wu:fc17a09 antikoerper, wu:fc17a10 antikoerper, wu:fj12e11 antikoerper, zgc:56601 antikoerper, znf207 antikoerper, wu:fa03f07 antikoerper, wu:fb51h09 antikoerper, zgc:77832 antikoerper, zinc finger protein 207 antikoerper, zinc finger protein 207, b antikoerper, zinc finger protein 207 S homeolog antikoerper, zinc finger protein 207, a antikoerper, Zfp207 antikoerper, znf207 antikoerper, ZNF207 antikoerper, znf207b antikoerper, znf207.S antikoerper, znf207a antikoerper

Hintergrund: Background: ZNF207 is a kinetochore- and microtubule-binding protein that plays a key role in spindle assembly. ZNF207/BuGZ is mainly composed of disordered low-complexity regions and undergoes phase transition or coacervation to form temperature-dependent liquid droplets. Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by concentrating its building blocks. Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetochore loading of BUB3. Mechanisms by which BUB3 is protected are unclear: according to a first report, ZNF207/BuGZ may act by blocking ubiquitination and proteasomal degradation of BUB3 . According to another report, the stabilization is independent of the proteasome. [taken from the Universal Protein Resource (UniProt) O43670].

Gen-ID: 7756

UniProt: O43670