VSX2 Antikörper (AA 251-361)

Produktnummer ABIN718976

Produktdetails anti-VSX2 Antikörper

Target: VSX2 (Visual System Homeobox 2 (VSX2))

Bindungsspezifität: AA 251-361

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VSX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CHX10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu VSX2

Target: VSX2 (Visual System Homeobox 2 (VSX2))

Andere Bezeichnung: CHX10 (VSX2 Produkte)

Hintergrund:

Synonyms: C elegans ceh 10 homeo domain containing homolog, Ceh 10 homeo domain containing homolog C. elegans, Ceh 10 homeo domain containing homolog, Ceh 10 homeodomain containing homolog, Ceh 10 homeodomain containing homolog C. elegans, Ceh10 homeo domain containing homolog, Ceh10 homeodomain containing homolog, CHX 10, Homeobox protein CHX 10, Homeobox protein CHX10, HOX 10, HOX10, MCOP 2, MCOP2, MCOPCB 3, MCOPCB3, RET 1, RET1, Vsx 2, Vsx2.

Background: CHX10 is a 40 kDa homeodomain protein of the paired-like class that is essential for development of the mammalian eye. Mutations in CHX10 cause microphthalmia, a cause of congenital blindness in humans, and the ocular retardation (or) phenotype in mice. In the developing mouse retina CHX10 is expressed in retinal progenitors, while in the mature retina, CHX10 expression becomes restricted to bipolar neurons. Concurrent with these expression patterns, the CHX10-/- (or) retina is thin due to a defect in proliferation of retinal progenitors, and lacks bipolar neurons. CHX10 is also expressed in the developing brainstem, thalamus, and spinal cord.

Gen-ID: 338917

Pathways: Dopaminergic Neurogenesis