CAND1 Antikörper (AA 1180-1230)
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- Target Alle CAND1 Antikörper anzeigen
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
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Bindungsspezifität
- AA 1180-1230
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CAND1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Verwendungszweck
- Rabbit anti-CAND1 Antibody, Affinity Purified
- Homologie
- Rat,Bovine,Orangutan
- Aufreinigung
- Affinity Purified
- Immunogen
- between AA 1180 and 1230
- Isotyp
- IgG
- Top Product
- Discover our top product CAND1 Primärantikörper
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anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1-100) antibody
CAND1 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 5D7 unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1-100) antibodyCAND1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 4D10 unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1-100) antibodyCAND1 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1-100) antibodyCAND1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 5F2 unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 750-980) antibodyCAND1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1150-1230) antibodyCAND1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) antibodyCAND1 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (C-Term) antibodyCAND1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd, Kaninchen, Zebrafisch (Danio rerio), Schwein, Fledermaus, Hamster, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 112-161) antibodyCAND1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd, Kaninchen, Zebrafisch (Danio rerio), Schwein, Fledermaus, Huhn, Hamster, Affe, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1180-1230) antibodyCAND1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Huhn WB, IHC, IP, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
- Andere Bezeichnung
- CAND1 (CAND1 Produkte)
- Hintergrund
- Background: Cullin-associated NEDD8-dissociated protein 1 (CAND1) is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site and disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins. CAND1 also binds TATA binding protein and enhances transcription from various promoters [taken from the Universal Protein Resource (UniProt) Q86VP6].
- Gen-ID
- 55832
- NCBI Accession
- NP_060918
- UniProt
- Q86VP6
- Pathways
- Regulation of Actin Filament Polymerization
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