POLE3 Antikörper (AA 97-147)

Produktnummer ABIN7453486

Produktdetails anti-POLE3 Antikörper

Target: POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))

Bindungsspezifität: AA 97-147

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLE3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-PolE3/p17 Antibody, Affinity Purified

Homologie: Rat,Bovine,Orangutan

Aufreinigung: Affinity Purified

Immunogen: between AA 97 and 147

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu POLE3

Target: POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))

Andere Bezeichnung: PolE3/p17 (POLE3 Produkte)

Synonyme: NCU04548.1 antikoerper, GB14966 antikoerper, zgc:73351 antikoerper, 1810034K18Rik antikoerper, YBL1 antikoerper, CHARAC17 antikoerper, CHRAC17 antikoerper, p17 antikoerper, DNA polymerase epsilon 3, accessory subunit antikoerper, polymerase (DNA directed), epsilon 3, accessory subunit antikoerper, DNA polymerase epsilon antikoerper, DNA polymerase epsilon p17 subunit antikoerper, DNA polymerase epsilon subunit 3 antikoerper, polymerase (DNA directed), epsilon 3 (p17 subunit) antikoerper, POLE3 antikoerper, pole3 antikoerper, NCU04548 antikoerper, CpipJ_CPIJ008666 antikoerper, Bm1_04865 antikoerper, Bm1_07285 antikoerper, CTRG_00708 antikoerper, LOAG_09571 antikoerper, LOC726923 antikoerper, Pole3 antikoerper

Hintergrund: Background: PolE3/p17 is a subunit of DNA polymerase epsilon that plays a role in DNA replication and repair. PolE3/p17 contains histone-fold motifs which play a role in protein-protein and protein-DNA interactions. PolE3/p17 interacts with CHRAC1 (chromatin assembly complex 1), ACF1, and ISWI/SNF2H proteins to form the CHRAC ISWI chromatin-remodeling complex.

Gen-ID: 54107

NCBI Accession: NP_059139

UniProt: Q9NRF9

Pathways: DNA Reparatur