RBM17 Antikörper (AA 25-75)

Produktnummer ABIN7453552

Produktdetails anti-RBM17 Antikörper

Target: RBM17 (RNA Binding Motif Protein 17 (RBM17))

Bindungsspezifität: AA 25-75

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-SPF45 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 25 and 75

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-SPF45 antibody ABIN7453790.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu RBM17

Target: RBM17 (RNA Binding Motif Protein 17 (RBM17))

Andere Bezeichnung: SPF45 (RBM17 Produkte)

Synonyme: zgc:55840 antikoerper, SPF45 antikoerper, 2700027J02Rik antikoerper, RNA binding motif protein 17 antikoerper, RNA binding motif protein 17 L homeolog antikoerper, Rbm17 antikoerper, rbm17 antikoerper, RBM17 antikoerper, rbm17.L antikoerper

Hintergrund: Background: Splicing factor 45 (SPF45) is an RNA splicing factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. SPF45 is involved in the regulation of alternative splicing and the utilization of cryptic splice sites. It has been shown to promote the utilization of a cryptic splice site created by the beta-110 mutation in the human beta-thalassemia gene. The resulting frameshift leads to sickle cell anemia [taken from the Universal Protein Resource (UniProt) Q96125].

Gen-ID: 84991

NCBI Accession: NP_116294

UniProt: Q96I25