PSMD1 Antikörper (AA 903-953)
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- Target Alle PSMD1 Antikörper anzeigen
- PSMD1 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 1 (PSMD1))
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Bindungsspezifität
- AA 903-953
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PSMD1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Verwendungszweck
- Rabbit anti-PSMD1 Antibody, Affinity Purified
- Homologie
- Rat,Chicken,Orangutan
- Aufreinigung
- Affinity Purified
- Immunogen
- between AA 903 and 953
- Isotyp
- IgG
- Top Product
- Discover our top product PSMD1 Primärantikörper
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- Applikationshinweise
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IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:25,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- PSMD1 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 1 (PSMD1))
- Andere Bezeichnung
- PSMD1 (PSMD1 Produkte)
- Synonyme
- P112 antikoerper, Rpn2 antikoerper, S1 antikoerper, 2410026J11Rik antikoerper, zgc:55818 antikoerper, psmd1 antikoerper, proteasome 26S subunit, non-ATPase 1 antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 antikoerper, proteasome 26S subunit, non-ATPase 1 L homeolog antikoerper, PSMD1 antikoerper, Psmd1 antikoerper, psmd1 antikoerper, psmd1.L antikoerper
- Hintergrund
- Background: PSMD1 [proteasome (prosome, macropain) 26S subunit, non-ATPase, 1] is a subunit of the 26 S proteasome. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD1 is the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding [taken from NCBI Entrez Gene (Gene ID: 5707)].
- Gen-ID
- 5707
- NCBI Accession
- NP_002798
- UniProt
- Q99460
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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