CHD8 Antikörper (AA 325-350)

Produktnummer ABIN7453579

Produktdetails anti-CHD8 Antikörper

Target: CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))

Bindungsspezifität: AA 325-350

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHD8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-CHD8 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 325 and 350

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu CHD8

Target: CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))

Andere Bezeichnung: CHD8 (CHD8 Produkte)

Synonyme: CHD8 antikoerper, Chd8 antikoerper, CHD-8 antikoerper, AUTS18 antikoerper, HELSNF1 antikoerper, 5830451P18Rik antikoerper, AU015341 antikoerper, Duplin antikoerper, mKIAA1564 antikoerper, fi45h08 antikoerper, si:ch211-10e2.6 antikoerper, wu:fi45h08 antikoerper, chromodomain helicase DNA binding protein 8 antikoerper, CHD8 antikoerper, chd8 antikoerper, Chd8 antikoerper

Hintergrund: Background: CHD8 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD8 has been reported to interact with duplin, a protein involved in the wnt signaling pathway, and CTCF, a protein involved in heterochromatin formation.

Gen-ID: 57680

NCBI Accession: NP_065971

UniProt: Q9HCK8

Pathways: Chromatin Binding