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MSK2 Antikörper (AA 722-772)

RPS6KA4 Reaktivität: Human, Maus WB, IP, IHC (fp) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7453734
  • Target Alle MSK2 (RPS6KA4) Antikörper anzeigen
    MSK2 (RPS6KA4) (Ribosomal Protein S6 Kinase A4 (RPS6KA4))
    Bindungsspezifität
    • 10
    • 9
    • 7
    • 7
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 722-772
    Reaktivität
    • 60
    • 48
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 59
    • 2
    Kaninchen
    Klonalität
    • 59
    • 2
    Polyklonal
    Konjugat
    • 24
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Dieser MSK2 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 22
    • 11
    • 9
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    Verwendungszweck
    Rabbit anti-MSK2 Antibody, Affinity Purified
    Aufreinigung
    Affinity Purified
    Immunogen
    between AA 722 and 772
    Isotyp
    IgG
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    Discover our top product RPS6KA4 Primärantikörper
  • Applikationshinweise

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    MSK2 (RPS6KA4) (Ribosomal Protein S6 Kinase A4 (RPS6KA4))
    Andere Bezeichnung
    MSK2 (RPS6KA4 Produkte)
    Synonyme
    MSK2 antikoerper, RSK-B antikoerper, 1110069D02Rik antikoerper, 90kDa antikoerper, AI848992 antikoerper, Msk2 antikoerper, mMSK2 antikoerper, ribosomal protein S6 kinase A4 antikoerper, ribosomal protein S6 kinase, polypeptide 4 antikoerper, RPS6KA4 antikoerper, Rps6ka4 antikoerper
    Hintergrund
    Background: MSK1 is a serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). MSK1 Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. MSK1 also phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. [taken from the Universal Protein Resource (UniProt) O75582].
    Gen-ID
    8986
    NCBI Accession
    NP_003933
    UniProt
    O75676
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