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UBR4 Antikörper (AA 5133-5183)

UBR4 Reaktivität: Human WB, IP, IHC (fp) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7453830
  • Target Alle UBR4 Antikörper anzeigen
    UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
    Bindungsspezifität
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 5133-5183
    Reaktivität
    • 23
    • 13
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 18
    • 4
    • 1
    Kaninchen
    Klonalität
    • 20
    • 3
    Polyklonal
    Konjugat
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UBR4 Antikörper ist unkonjugiert
    Applikation
    • 11
    • 9
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    Verwendungszweck
    Rabbit anti-p600 Antibody, Affinity Purified
    Homologie
    Mouse,Rat
    Aufreinigung
    Affinity Purified
    Immunogen
    between AA 5133 and 5183
    Isotyp
    IgG
    Top Product
    Discover our top product UBR4 Primärantikörper
  • Applikationshinweise

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: Not recommended. Use rabbit anti-p600 antibody A302-277A or A302-278A.

    WB: 1:2,000 - 1:10,000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
    Andere Bezeichnung
    p600 (UBR4 Produkte)
    Hintergrund
    Background: p600 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. It recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, p600 forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Additionally p600 regulates integrin-mediated signaling and may play a role in activation of FAK in response to cell-matrix interactions [taken from the Universal Protein Resource (UniProt) Q5T4S7].
    Gen-ID
    23352
    NCBI Accession
    NP_065816
    UniProt
    Q5T4S7
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