Rekombinanter PD-L1 Antikörper (C-Term)
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- Target Alle PD-L1 Antikörper anzeigen
- PD-L1 (CD274 (PD-L1))
- Antikörpertyp
- Recombinant Antibody
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser PD-L1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (fixed cells) (IF/ICC), Multiplex Immunofluorescence (mIF)
- Verwendungszweck
- Rabbit anti-PD-L1 Recombinant Monoclonal Antibody [BLR020E]
- Immunogen
- between AA 250 to 290 (C-term)
- Klon
- BLR020E
- Isotyp
- IgG
- Top Product
- Discover our top product PD-L1 Primärantikörper
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anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 Reaktivität: Human WB, FACS, ELISA, IF Wirt: Ziege Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 19-238) antibodyPD-L1 Reaktivität: Human WB, FACS, IHC, ELISA, IF Wirt: Maus Monoclonal 9B5F4 unconjugated
anti-CD274 (PD-L1) (AA 24-153) antibodyPD-L1 Reaktivität: Human FACS, IHC, ELISA Wirt: Maus Monoclonal 6D9A2 unconjugated
anti-CD274 (PD-L1) (AA 39-191) antibodyPD-L1 Reaktivität: Human, Maus WB, FACS, IHC, ELISA, IF, Coat, StM Wirt: Maus Monoclonal PDL1-2746 unconjugated
anti-CD274 (PD-L1) (AA 48-290) antibodyPD-L1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD274 (PD-L1) (Extracellular Domain) antibodyPD-L1 Reaktivität: Human IHC Wirt: Kaninchen Monoclonal unconjugated
anti-CD274 (PD-L1) (AA 34-241) antibodyPD-L1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 24-153) antibodyPD-L1 Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 7D2A10 unconjugated
anti-CD274 (PD-L1) (C-Term) antibodyKO Validated PD-L1 Reaktivität: Human WB, FACS, ICC, IF, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 19-238) antibodyPD-L1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1000 μg/mL
- Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- PD-L1 (CD274 (PD-L1))
- Andere Bezeichnung
- PD-L1 (PD-L1 Produkte)
- Hintergrund
- Background: PD-L1 is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. PD-L1 is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma [taken from NCBI Entrez Gene (Gene ID: 55193)].
- Gen-ID
- 29126
- NCBI Accession
- NP_054862
- UniProt
- Q9NZQ7
- Pathways
- Cancer Immune Checkpoints
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