NHEJ1 Antikörper (AA 200-250)

Produktnummer ABIN7454372

Produktdetails anti-NHEJ1 Antikörper

Target: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Bindungsspezifität: AA 200-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NHEJ1 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-XLF Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 200 and 250

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-XLF antibody A300-730A.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu NHEJ1

Target: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Andere Bezeichnung: XLF (NHEJ1 Produkte)

Synonyme: NHEJ1 antikoerper, zgc:85657 antikoerper, XLF antikoerper, 1700029B21Rik antikoerper, cernunnos antikoerper, non-homologous end joining factor 1 antikoerper, non-homologous end joining factor 1 S homeolog antikoerper, solute carrier family 23 member 3 antikoerper, nonhomologous end-joining factor 1 antikoerper, NHEJ1 antikoerper, nhej1.S antikoerper, nhej1 antikoerper, SLC23A3 antikoerper, Nhej1 antikoerper

Hintergrund: Background: XRCC4-like factor (XLF) functions in DNA nonhomologous end joining (NHEJ) in double-strand break repair and immune system V(D)J recombination. Mutations of XLF in humans have been documented to result in immunodeficiency, growth retardation, and microcephaly. The yeast of homolog of XLF is Nej1. XLF has been shown to interact with the XRCC4 x DNA-ligase IV complex and is implicated in the DNA religation step of the NHEJ pathway.

Gen-ID: 79840

NCBI Accession: NP_079058

UniProt: Q9H9Q4

Pathways: DNA Reparatur