KDM4A Antikörper (AA 350-400)
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- Target Alle KDM4A Antikörper anzeigen
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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Bindungsspezifität
- AA 350-400
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KDM4A Antikörper ist unkonjugiert
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Applikation
- Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Verwendungszweck
- Rabbit anti-JMJD2A Antibody, Affinity Purified
- Homologie
- Orangutan
- Aufreinigung
- Affinity Purified
- Immunogen
- between AA 350 and 400
- Isotyp
- IgG
- Top Product
- Discover our top product KDM4A Primärantikörper
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- Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-JMJD2A antibody A300-861A.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
- Andere Bezeichnung
- JMJD2A (KDM4A Produkte)
- Synonyme
- JMJD2A antikoerper, JHDM3A antikoerper, JMJD2 antikoerper, TDRD14A antikoerper, D4Ertd222e antikoerper, Jmjd2 antikoerper, Jmjd2a antikoerper, mKIAA0677 antikoerper, lysine demethylase 4A antikoerper, lysine-specific demethylase 4A antikoerper, lysine (K)-specific demethylase 4A antikoerper, KDM4A antikoerper, LOC100228023 antikoerper, Kdm4a antikoerper
- Hintergrund
- Background: JMJD2A is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD2A is a trimethylation-specific demethylase and functions as a transcriptional repressor. JMJD2A interacts with pRb and class one histone deacetylases to mediate repression of E2F-regulated promoters.
- Gen-ID
- 9682
- NCBI Accession
- NP_055478
- UniProt
- O75164
- Pathways
- Warburg Effekt
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