OSR1 Antikörper (AA 325-375)

Produktnummer ABIN7454414

Produktdetails anti-OSR1 Antikörper

Target: OSR1 (Odd-Skipped Related 1 (OSR1))

Bindungsspezifität: AA 325-375

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OSR1 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-OSR1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 325 and 375

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-OSR1 antibody A301-579A.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu OSR1

Target: OSR1 (Odd-Skipped Related 1 (OSR1))

Andere Bezeichnung: OSR1 (OSR1 Produkte)

Synonyme: XOsr1 antikoerper, odd antikoerper, odd1 antikoerper, znf91 antikoerper, ODD antikoerper, Odd1 antikoerper, Osr antikoerper, OXSR1 antikoerper, zgc:101674 antikoerper, odd-skipped related transciption factor 1 antikoerper, odd-skipped related 1 (Drosophila) antikoerper, OSR1 antikoerper, osr1 antikoerper, Osr1 antikoerper

Hintergrund: Background: Oxidative stress responsive 1 (OSR1) is a STE20-related kinase involved in ion transport and fluid and ion homeostasis. OSR1 interacts with SPAK (STE20/SPS1-reated proline/alanine-rich kinase) and together are activated by the upstream kinase WNK1 [with no K (lysine) protein kinase-1]. Activation of OSR1 and SPAK by WNK1 results in the phosphorylation and activation of NKCC1 (Na+-K+-2Cl- co-transporter 1) for the control of cell volume and blood pressure.

Gen-ID: 9943

NCBI Accession: NP_005100

UniProt: O95747

Pathways: Tube Formation