PAGR1 Antikörper (AA 204-254)

Produktnummer ABIN7454425

Produktdetails anti-PAGR1 Antikörper

Target: PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))

Bindungsspezifität: AA 204-254

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAGR1 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-PA1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 204 and 254

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-PA1 antibody A301-978A.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu PAGR1

Target: PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))

Andere Bezeichnung: PA1 (PAGR1 Produkte)

Synonyme: C16orf53 antikoerper, C25H16orf53 antikoerper, PA1 antikoerper, 2900092E17Rik antikoerper, C77040 antikoerper, PAGR1 antikoerper, GAS antikoerper, Pa1 antikoerper, PAXIP1 associated glutamate rich protein 1 antikoerper, PAXIP1 associated glutamate rich protein 1A antikoerper, Paxip1-associated glutamate-rich protein 1 antikoerper, PAGR1 antikoerper, Pagr1a antikoerper, Pagr1 antikoerper

Hintergrund: Background: PA1 (PTIP-associated protein 1) was isolated as a protein that associates with PTIP (Pax transactivation domain-interacting protein), a nuclear protein involved in the DNA damage response and interacts with the Pax2 transactivation domain. Along with PTIP, PA1 has been found to be present in a MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase complex. PA1 also appears to be important to the DNA damage response and repair. This involvement in DNA damage signaling is reported to be independent of its MLL association. PA1 has also been identified as GAS (glutamate-rich coactivator interacting with SRC1/NCOA1). As an interactor of SRC1 (steroid receptor coactivator 1), PA1 functions as a transcription cofactor.

Gen-ID: 79447

NCBI Accession: NP_078792

UniProt: Q9BTK6