LAS1L Antikörper (AA 200-250)

Produktnummer ABIN7454509

Produktdetails anti-LAS1L Antikörper

Target: LAS1L (LAS1-Like (LAS1L))

Bindungsspezifität: AA 200-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LAS1L Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-LAS1L Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 200 and 250

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu LAS1L

Target: LAS1L (LAS1-Like (LAS1L))

Andere Bezeichnung: LAS1L (LAS1L Produkte)

Synonyme: RGD1565755 antikoerper, Las1-like antikoerper, dJ475B7.2 antikoerper, 1810030A06Rik antikoerper, 5830482G23Rik antikoerper, LAS1-like, ribosome biogenesis factor antikoerper, LAS1 like, ribosome biogenesis factor antikoerper, LAS1-like (S. cerevisiae) antikoerper, Las1l antikoerper, LAS1L antikoerper

Hintergrund: Background: LAS1L is involved in the biogenesis of the 60S ribosomal subunit. It is required for maturation of the 28S rRNA. LAS1L functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes [taken from the Universal Protein Resource (UniProt) Q9Y4W2].

Gen-ID: 81887

NCBI Accession: NP_112483

UniProt: Q9Y4W2