Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

AKAP8L Antikörper (AA 596-646)

AKAP8L Reaktivität: Human WB, IP, IHC (fp) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7454742
  • Target Alle AKAP8L Antikörper anzeigen
    AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))
    Bindungsspezifität
    • 10
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 596-646
    Reaktivität
    • 37
    • 13
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 37
    Kaninchen
    Klonalität
    • 37
    Polyklonal
    Konjugat
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AKAP8L Antikörper ist unkonjugiert
    Applikation
    • 27
    • 18
    • 8
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    Verwendungszweck
    Rabbit anti-AKAP8L/HA95 Antibody, Affinity Purified
    Aufreinigung
    Affinity Purified
    Immunogen
    between AA 596 and 646
    Isotyp
    IgG
    Top Product
    Discover our top product AKAP8L Primärantikörper
  • Applikationshinweise

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))
    Andere Bezeichnung
    AKAP8L/HA95 (AKAP8L Produkte)
    Synonyme
    HA95 antikoerper, HAP95 antikoerper, NAKAP antikoerper, NAKAP95 antikoerper, Nakap95 antikoerper, zgc:85966 antikoerper, AKAP8L antikoerper, A-kinase anchoring protein 8 like antikoerper, A kinase (PRKA) anchor protein 8-like antikoerper, A-kinase anchoring protein 8 like L homeolog antikoerper, AKAP8L antikoerper, Akap8l antikoerper, akap8l antikoerper, akap8l.L antikoerper
    Hintergrund
    Background: AKAP8L/HA95 is a PKA anchoring protein that is localized to the nuclear envelope and associates with chromatin upon nuclear envelope breakdown during mitosis. AKAP8L/HA95 has been found to play an important role in the initiation of DNA replication and may function as a scaffold for proteins such as MCM2 and LAP2beta. Additionally, AKAP8L/HA95 has been shown to co-locate with the PKA C subunit in splicing factor compartments and is involved in the regulation of pre-mRNA splicing. Further support for a scaffolding and splicing role in the nucleus comes from the observation that AKAP8L/HA95 colocalizes with HypA, a splicing-like factor, and through this association may function as a docking site for the nuclear accumulation of Huntington protein as seen in Huntington's disease.
    Gen-ID
    26993
    NCBI Accession
    NP_055186
    UniProt
    Q9ULX6
    Pathways
    SARS-CoV-2 Protein Interaktom
Sie sind hier:
Kundenservice